Modulari-T Bioscience — From Molecule to Therapy
Next-Generation Cell & Gene Therapy · Canada

from  molecule to  therapy. science. hope.

Modulari-T designs modular synthetic immune receptors and proprietary in vivo delivery vectors — making cell therapy safer, more potent, and accessible to every patient.

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Who We Are.

Modulari-T Bioscience is a Montreal-based, McGill ecosystem biotech startup rewriting the rules of cell therapy. We combine natural immune receptor biology with cutting-edge AI protein design to engineer the next generation of therapeutic tools.

Our two core platforms — MARC and MoVE — work in tandem to overcome every critical failure point in existing CAR-T approaches: exhaustion, cost, manufacturing complexity, and limited immune cell targeting.

Discover Our Platforms
🧬
MARC Platform
🔬
MoVE Platform
MARC Platform
Synthetic immune receptors
MoVE Delivery
In vivo gene delivery
Oncology
T cell exhaustion prevention
AI Protein Design
Off-the-shelf therapy
Autoimmunity
NK cell targeting
JITC 2025
Peer-reviewed science
MARC Platform
Synthetic immune receptors
MoVE Delivery
In vivo gene delivery
Oncology
T cell exhaustion prevention
AI Protein Design
Off-the-shelf therapy
Autoimmunity
NK cell targeting
JITC 2025
Peer-reviewed science
Our Core Principles
🛡️
Safety
Efficacy
🔬
Precision
🤖
Innovation
🌍
Accessibility
🧪
Rigour
Platform 01 I
Core Technology

MARC
Modular Actuation
Receptor Cells

A synthetic immune receptor engineered to mirror the natural architecture of the T cell receptor — eliminating tonic signaling, preventing exhaustion, and delivering superior in vivo persistence across any cell type.

T Cell Exhaustion Prevention Enhanced Persistence Multi-Target Ready Best-in-class Safety AI-Optimized
See the Science
Platform 02 II
Delivery Platform

MoVE
Modular Vector
Platform

Immune cell-specific vectors injected intravenously — finding, activating, and genetically reprogramming target immune cells directly inside the patient's body. No lab. No delay. Just therapy.

IV Injection Only T & NK Cell Targeting Liver-Safe Off-the-Shelf No Ex Vivo Processing
Learn More
Platform 03 III
🤖
Computational Layer

AI Protein
Design Engine

A proprietary computational platform that designs, predicts, and optimizes MARC variants for any therapeutic target — compressing years of wet-lab iteration into weeks of in silico engineering.

In Silico Optimization Binding Prediction Novel Variant Generation Accelerated Discovery
Our Approach

Numbers that matter.

Every milestone grounded in peer-reviewed science and real clinical biology.

50+
Publications
3
Therapeutic Areas
4
Cell Type Targets
2025
JITC Publication
Peer-Reviewed Validation

Backed by evidence.
Published in JITC.

Our foundational research demonstrates measurable, peer-validated superiority of MARC over conventional CAR architectures — in the world's leading immunotherapy journal.

Read Full Publication
Journal of Immunotherapy and Cancer · Vol. 13 · 2025
MARC, a novel modular chimeric antigen receptor, improves T cell-based cancer immunotherapies by preventing early T cell exhaustion and enhancing persistence.
Tual et al. — BMJ Publishing Group Ltd
IRIC · University of Montreal · Modulari-T Bioscience
Open in JITC

The Team.

Full Profiles
David
Co-Founder & CEO
David Cotnoir-White, PhD
CEO & Co-founder
Protein receptor architecture expert...
Stephanie
Co-Founder & COO
Stephanie Mok, PhD
COO & Co-founder
Chemical Engineering PhD, McGill...
Etienne
Co-Founder & CSO
Étienne Gagnon, PhD
CSO & Co-founder
Post-doc at Dana-Farber...
Delphine
Principal Scientist
Delphine Guipouy, PhD
Principal Scientist
Immunology PhD from INSERM...
Collaborate With Us

from idea
to action.

Whether you're an investor, pharma partner, or academic collaborator — we want to hear from you.

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